Power users sometimes use mklink to store STEAM on a different hard drive. If the drive letter changed (e.g., D: became E:), the patcher sees a broken link and fails.
Best regards,
In the context of Omnisphere, "patching" does refer to patching a crack or a hack (though many pirate-related forums discuss this error, it happens to legitimate users just as often). Instead, "patching" refers to the process of updating or modifying core application files to integrate with your system, your DAW, or a new update.
: If your DAW (Digital Audio Workstation) or a standalone version of Omnisphere is open, the system "locks" the files, making them unpatchable.
And then — silence. Not the good kind.