Do not place your Cathedral in the corner. Place it in the dead center of your main island.
[Harbor / Warehouse / Shipyard] → South coast [Market + Chapel + Pub] → Just inland from harbor [Peasant/Citizen blocks] → Southwest & Southeast [Patrician rows] → West & East mid-island [Noblemen quarters] → Central-north, elevated [Oriental Quarter (via Venetian Canal)] → Northeast corner [Production farm belt] → North & Northwest hills [Fortress / Keep] → On a hill overlooking harbor [Monastery / Cathedral] → Center near noblemen